Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders

Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders

Nucleotide-binding oligomerization domain 1 (NOD1) is an intracellular sensor that detects small peptides derived from the cell wall component of intestinal microflora. NOD1 is expressed in both non-hematopoietic cells such as epithelial cells and hematopoietic cells such as antigen-presenting cells. Detection of its ligand by NOD1 leads to innate immune responses through activation of nuclear ...

Nucleotide-Binding Oligomerization Domain

association of nucleotide-binding oligomerization domain receptors with peptic ulcer and gastric cancer

host innate immunity can affect the clinical outcomes of helicobacter pylori infection, including gastritis, gastric ulcer, gastric adenocarcinoma, and malt lymphoma. nucleotide binding oligomerization domain (nod)-1 and -2 are two molecules of innate immunity which are involved in the host defense against h. pylori . this study aimed to evaluate the effect of the expression level of nod1 and n...

Oligomerization Domain-like Receptor TLR and Nucleotide-Binding

Nucleotide-Binding Oligomerization